TGF-β Signaling in Cancer: Control by Negative Regulators and Crosstalk with Proinflammatory and Fibrogenic Pathways
The transforming growth factor-β (TGF-β) family of secreted growth factors controls many aspects of cell and tissue physiology in multicellular eukaryotes. Dysregulation of its pathway contributes to a broad variety of pathologies, including fibrosis and cancer. TGF-β acts...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-03-01
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| Series: | Cancers |
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| Online Access: | http://www.mdpi.com/2072-6694/11/3/384 |