Bispecific human IL2‐CCR4 immunotoxin targets human cutaneous T‐cell lymphoma

The majority of clinically diagnosed cutaneous T‐cell lymphomas (CTCL) highly express the cell‐surface markers CC chemokine receptor 4 (CCR4) and/or CD25. Recently, we have developed diphtheria toxin‐based recombinant Ontak®‐like human IL2 fusion toxin (IL2 fusion toxin) and anti‐human CCR4 immunoto...

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Bibliographic Details
Main Authors: Haoyu Wang, Zhaohui Wang, Huiping Zhang, Zeng Qi, Ariel C. Johnson, David Mathes, Elizabeth A. Pomfret, Erin Rubin, Christene A. Huang, Zhirui Wang
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:Molecular Oncology
Subjects:
IL2
Online Access:https://doi.org/10.1002/1878-0261.12653