Association of TIMP4 gene variants with steroid-induced osteonecrosis of the femoral head in the population of northern China

Association of TIMP4 gene variants with steroid-induced osteonecrosis of the femoral head in the population of northern China

Background In clinical treatment, the use of steroid hormones is an important etiological factor of non-traumatic osteonecrosis of the femoral head (ONFH) risk. As an endogenous inhibitor of matrix metalloproteinases (MMPs) in the extracellular matrix, the expression of tissue inhibitors of metallop...

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Bibliographic Details
Main Authors: Jiaqi Wang, Feimeng An, Yuju Cao, Hongyan Gao, Mingqi Sun, Chao Ma, Hao Wu, Baoxin Zhang, Wanlin Liu, Jianzhong Wang
Format: Article
Language:English
Published: PeerJ Inc. 2019-01-01
Series:PeerJ
Subjects:
Tissue inhibitors of metalloprotease-4
Osteonecrosis of the femoral head
Single-nucleotide polymorphisms
Gene variants
Clinical phenotypes
Association study
Online Access:https://peerj.com/articles/6270.pdf

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https://peerj.com/articles/6270.pdf

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