SDF1-a facilitates Lin-/Sca1+ cell homing following murine experimental cerebral ischemia.

BACKGROUND: Hematopoietic stem cells mobilize to the peripheral circulation in response to stroke. However, the mechanism by which the brain initiates this mobilization is uncharacterized. METHODS: Animals underwent a murine intraluminal filament model of focal cerebral ischemia and the SDF1-A pathw...

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Bibliographic Details
Main Authors: J Mocco, Aqeela Afzal, Saeed Ansari, Annemarie Wolfe, Kenneth Caldwell, E S Connolly, Edward W Scott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3896412?pdf=render