Inference of kinase-signaling networks in human myeloid cell line models by Phosphoproteomics using kinase activity enrichment analysis (KAEA)

Inference of kinase-signaling networks in human myeloid cell line models by Phosphoproteomics using kinase activity enrichment analysis (KAEA)

Abstract Background Despite the introduction of targeted therapies, most patients with myeloid malignancies will not be cured and progress. Genomics is useful to elucidate the mutational landscape but remains limited in the prediction of therapeutic outcome and identification of targets for resistan...

Full description

Bibliographic Details
Main Authors: Mahmoud Hallal, Sophie Braga-Lagache, Jovana Jankovic, Cedric Simillion, Rémy Bruggmann, Anne-Christine Uldry, Ramanjaneyulu Allam, Manfred Heller, Nicolas Bonadies
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Cancer
Subjects:
Phosphoproteomics
Kinase activity
Kinase-signaling network
Myeloid malignancies
Online Access:https://doi.org/10.1186/s12885-021-08479-z

Internet

https://doi.org/10.1186/s12885-021-08479-z

Similar Items