Regulation of endothelial-specific transgene expression by the LacI repressor protein in vivo.

Genetically modified mice have played an important part in elucidating gene function in vivo. However, conclusions from transgenic studies may be compromised by complications arising from the site of transgene integration into the genome and, in inducible systems, the non-innocuous nature of inducer...

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Bibliographic Details
Main Authors: Susan K Morton, Daniel J Chaston, Brett K Baillie, Caryl E Hill, Klaus I Matthaei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3995964?pdf=render