H3F3A-G34R mutant high grade neuroepithelial neoplasms with glial and dysplastic ganglion cell components

H3F3A-G34R mutant high grade neuroepithelial neoplasms with glial and dysplastic ganglion cell components

Abstract The recently described malignant neuro-epithelial tumors with histone H3F3A point mutations at G34 (NET-H3-G34) occur most often in cerebral hemispheres of teenagers and young adults, and have a generally adverse prognosis. These tumors have been histologically classified as glioblastoma or...

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Bibliographic Details
Main Authors: Felipe Andreiuolo, Tomo Lisner, Jozef Zlocha, Christof Kramm, Arend Koch, Brigitte Bison, Albane Gareton, Marc Zanello, Andreas Waha, Pascale Varlet, Torsten Pietsch
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Acta Neuropathologica Communications
Subjects:
Anaplastic ganglioglioma
Histone H3
Mutation
G34R
Neuroepithelial tumor
Glioblastoma
Online Access:http://link.springer.com/article/10.1186/s40478-019-0731-5

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http://link.springer.com/article/10.1186/s40478-019-0731-5

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