Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H. F. Chou Seed Ameliorates Insomnia in Rats by Regulating Metabolomics and Intestinal Flora Composition

Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H. F. Chou Seed Ameliorates Insomnia in Rats by Regulating Metabolomics and Intestinal Flora Composition

The seed of Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H. F. Chou (ZSS) is often used as a traditional Chinese medicine for insomnia due to its sedative and hypnotic effects, but the mechanism underlying this effect has not been thoroughly elucidated. In this study, an insomnia model induced b...

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Bibliographic Details
Main Authors: Yue Hua, Sheng Guo, Hong Xie, Yue Zhu, Hui Yan, Wei-wei Tao, Er-xin Shang, Da-wei Qian, Jin-ao Duan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
insomnia
Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H. F. Chou seed
metabolomics
intestinal flora
short-chain fatty acid
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.653767/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.653767/full

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