Increased Transfection of the Easily Oxidizable GC-Rich DNA Fragments into the MCF7 Breast Cancer Cell

Objective. Easily oxidizable GC-rich DNA (GC-DNA) fragments accumulate in the cell-free DNA (cfDNA) of patients with various diseases. The human oxidized DNA penetrates the MCF7 breast cancer cells and significantly changes their physiology. It can be assumed that readily oxidizable GC-DNA fragments...

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Bibliographic Details
Main Authors: Svetlana V. Kostyuk, Nadezhda N. Mordkovich, Natalya A. Okorokova, Vladimir P. Veiko, Elena M. Malinovskaya, Elizaveta S. Ershova, Marina S. Konkova, Ekaterina A. Savinova, Maria A. Borzikova, Tatiana A. Muzaffarova, Lev N. Porokhovnik, Nataly N. Veiko, Serguey I. Kutsev
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/2348165