Production of an attenuated phenol-soluble modulin variant unique to the MRSA clonal complex 30 increases severity of bloodstream infection.

Production of an attenuated phenol-soluble modulin variant unique to the MRSA clonal complex 30 increases severity of bloodstream infection.

Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of morbidity and death. Phenol-soluble modulins (PSMs) are recently-discovered toxins with a key impact on the development of Staphylococcus aureus infections. Allelic variants of PSMs and their potential impact on pathogen succes...

Full description

Bibliographic Details
Main Authors: Gordon Y C Cheung, Dorothee Kretschmer, Anthony C Duong, Anthony J Yeh, Trung V Ho, Yan Chen, Hwang-Soo Joo, Barry N Kreiswirth, Andreas Peschel, Michael Otto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4140855?pdf=render

Internet

http://europepmc.org/articles/PMC4140855?pdf=render

Similar Items