Sequestration of host metabolism by an intracellular pathogen

Sequestration of host metabolism by an intracellular pathogen

For intracellular pathogens, residence in a vacuole provides a shelter against cytosolic host defense to the cost of limited access to nutrients. The human pathogen Chlamydia trachomatis grows in a glycogen-rich vacuole. How this large polymer accumulates there is unknown. We reveal that host glycog...

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Bibliographic Details
Main Authors: Lena Gehre, Olivier Gorgette, Stéphanie Perrinet, Marie-Christine Prevost, Mathieu Ducatez, Amanda M Giebel, David E Nelson, Steven G Ball, Agathe Subtil
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-03-01
Series:eLife
Subjects:
chlamydia trachomatis
host-pathogen interactions
intracellular parasites
glycogen metabolism
Online Access:https://elifesciences.org/articles/12552

Internet

https://elifesciences.org/articles/12552

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