Neonatal Clonazepam Administration Induces Long-Lasting Changes in Glutamate Receptors

Neonatal Clonazepam Administration Induces Long-Lasting Changes in Glutamate Receptors

γ-aminobutyric acid (GABA) pathways play an important role in neuronal circuitry formation during early postnatal development. Our previous studies revealed an increased risk for adverse neurodevelopmental consequences in animals exposed to benzodiazepines, which enhance GABA inhibition via GABAA re...

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Bibliographic Details
Main Authors: Hana Kubová, Zdenka Bendová, Simona Moravcová, Dominika Pačesová, Luisa Lilia Rocha, Pavel Mareš
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
neonatal rat
benzodiazepine
clonazepam
NMDA receptor subunits
AMPA receptor subunits
mRNA expression
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00382/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00382/full

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