Single nucleotide polymorphism analysis of European archaeological M. leprae DNA.

BACKGROUND:Leprosy was common in Europe eight to twelve centuries ago but molecular confirmation of this has been lacking. We have extracted M. leprae ancient DNA (aDNA) from medieval bones and single nucleotide polymorphism (SNP) typed the DNA, this provides insight into the pattern of leprosy tran...

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Bibliographic Details
Main Authors: Claire L Watson, Diana N J Lockwood
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2761613?pdf=render