Fast and accurate haplotype frequency estimation for large haplotype vectors from pooled DNA data

<p>Abstract</p> <p>Background</p> <p>Typically, the first phase of a genome wide association study (GWAS) includes genotyping across hundreds of individuals and validation of the most significant SNPs. Allelotyping of pooled genomic DNA is a common approach to reduce th...

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Bibliographic Details
Main Authors: Iliadis Alexandros, Anastassiou Dimitris, Wang Xiaodong
Format: Article
Language:English
Published: BMC 2012-10-01
Series:BMC Genetics
Online Access:http://www.biomedcentral.com/1471-2156/13/94