Total flavones of Abelmoschus manihot improve diabetic nephropathy by inhibiting the iRhom2/TACE signalling pathway activity in rats

Context: Total flavones extracted from Abelmoschus manihot L. (Malvaceae) medic (TFA) have been proven clinically effective at improving renal inflammation and glomerular injury in chronic kidney disease (CKD). Objective: This study evaluated the function of TFA as an inhibitor of iRhom2/TACE (tumou...

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Bibliographic Details
Main Authors: Su Liu, Lifang Ye, Jing Tao, Chao Ge, Liji Huang, Jiangyi Yu
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Pharmaceutical Biology
Subjects:
tfa
Online Access:http://dx.doi.org/10.1080/13880209.2017.1412467