Are zinc-bound metallothionein isoforms (I+II and III) involved in impaired thymulin production and thymic involution during ageing?

Are zinc-bound metallothionein isoforms (I+II and III) involved in impaired thymulin production and thymic involution during ageing?

<p>Abstract</p> <p>Background</p> <p>With advancing age, thymic efficiency shows progressive decline due to thymic involution allowing impaired cell-mediated immunity and the appearance of age-related diseases. The intrinsic cause of thymic involution is still undefined...

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Bibliographic Details
Main Authors: Cipriano Catia, Giacconi Robertina, Mocchegiani Eugenio, Muti Elisa, Gasparini Nazzarena, Malavolta Marco
Format: Article
Language:English
Published: BMC 2004-11-01
Series:Immunity & Ageing
Subjects:
Thymic involution
Metallothioneins
IL-6
glucocorticoids
zinc
TECs
inflammation
ageing
longevity
Online Access:http://www.immunityageing.com/content/1/1/5

Internet

http://www.immunityageing.com/content/1/1/5

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