Confining the Concept of Vascular Depression to Late-Onset Depression: A Meta-Analysis of MRI-Defined Hyperintensity Burden in Major Depressive Disorder and Bipolar Disorder

Confining the Concept of Vascular Depression to Late-Onset Depression: A Meta-Analysis of MRI-Defined Hyperintensity Burden in Major Depressive Disorder and Bipolar Disorder

Background: The vascular depression hypothesis emphasizes the significance of vascular lesions in late-life depression. At present, no meta-analytic model has investigated whether a difference in hyperintensity burden compared to controls between late-life and late-onset depression is evident. By in...

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Bibliographic Details
Main Authors: Katharina I. Salo, Jana Scharfen, Isabelle D. Wilden, Ricarda I. Schubotz, Heinz Holling
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Psychology
Subjects:
white matter hyperintensities (WMH)
leukoaraiosis
major depressive disorder
bipolar disorder
depression
cerebrovascular pathology
Online Access:https://www.frontiersin.org/article/10.3389/fpsyg.2019.01241/full

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https://www.frontiersin.org/article/10.3389/fpsyg.2019.01241/full

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