Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain

Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain

Lipid droplets (LDs) are fat storage organelles that are initiated and expanded by seipins at ER contact sites. Here the authors show that the C. elegans seipin ortholog SEIP-1 is recruited to these sites by certain dietary fatty acids to support the expansion of a subset of LDs.

Bibliographic Details
Main Authors: Zhe Cao, Yan Hao, Chun Wing Fung, Yiu Yiu Lee, Pengfei Wang, Xuesong Li, Kang Xie, Wen Jiun Lam, Yifei Qiu, Ben Zhong Tang, Guanghou Shui, Pingsheng Liu, Jianan Qu, Byung-Ho Kang, Ho Yi Mak
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10835-4

Internet

https://doi.org/10.1038/s41467-019-10835-4

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