ENCAPSULATION INTO STEALTH LIPOSOMES ENHANCED THE ANTITUMOR ACTION OF RECOMBINANT Cratylia mollis LECTIN EXPRESSED IN Escherichia coli

ENCAPSULATION INTO STEALTH LIPOSOMES ENHANCED THE ANTITUMOR ACTION OF RECOMBINANT Cratylia mollis LECTIN EXPRESSED IN Escherichia coli

This study evaluated the in vivo antitumor potential of new recombinant lectin from seeds of Cratylia mollis (rCramoll) expressed in Escherichia coli, free or encapsulated in stealth liposomes, using mice transplanted with sarcoma 180. rCramoll-loaded stealth liposomes (rCramoll-lipo) were formulate...

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Bibliographic Details
Main Authors: Cássia Regina Albuquerque da Cunha, Luis Cláudio Nascimento Da Silva, Fábio José Fidélis Almeida, Milena Sales Ferraz, Nathalia Varejão, Marina Falcão de Souza Cartaxo, Rita De Cássia Mendonça De Miranda, Francisco Carlos Amanajás de Aguiar Júnior, Noemia Pereira da Silva Santos, Luana Cassandra Breitenbach Barroso Coelho, Nereide Stela Santos-Magalhães, Maria Tereza dos Santos Correia
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Microbiology
Subjects:
Immunomodulation
Lectins
Pharmaceutical Preparations
Cancer
heterologous expression
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01355/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01355/full

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