Sequence evolution of the intrinsically disordered and globular domains of a model viral oncoprotein.
In the present work, we have used the papillomavirus E7 oncoprotein to pursue structure-function and evolutionary studies that take into account intrinsic disorder and the conformational diversity of globular domains. The intrinsically disordered (E7N) and globular (E7C) domains of E7 show similar d...
Main Authors: | Lucía B Chemes, Juliana Glavina, Leonardo G Alonso, Cristina Marino-Buslje, Gonzalo de Prat-Gay, Ignacio E Sánchez |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3485249?pdf=render |
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