Functional analysis of Tcl1 using Tcl1-deficient mouse embryonic stem cells.

Functional analysis of Tcl1 using Tcl1-deficient mouse embryonic stem cells.

Tcl1 is highly expressed in embryonic stem (ES) cells, but its expression rapidly decreases following differentiation. To assess Tcl1's roles in ES cells, we generated Tcl1-deficient and -overexpressing mouse ES cell lines. We found that Tcl1 was neither essential nor sufficient for maintaining...

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Bibliographic Details
Main Authors: Tatsushi Miyazaki, Satsuki Miyazaki, Masafumi Ashida, Tomofumi Tanaka, Fumi Tashiro, Jun-ichi Miyazaki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3733782?pdf=render

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http://europepmc.org/articles/PMC3733782?pdf=render

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