The adipokinetic hormones and their cognate receptor from the desert locust, Schistocerca gregaria: solution structure of endogenous peptides and models of their binding to the receptor

Background Neuropeptides exert their activity through binding to G protein-coupled receptors (GPCRs). GPCRs are well-known drug targets in the pharmaceutical industry and are currently discussed as targets to control pest insects. Here, we investigate the neuropeptide adipokinetic hormone (AKH) syst...

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Bibliographic Details
Main Authors: Graham E. Jackson, Elumalai Pavadai, Gerd Gäde, Niels H. Andersen
Format: Article
Language:English
Published: PeerJ Inc. 2019-08-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/7514.pdf