Lysosome activity is modulated by multiple longevity pathways and is important for lifespan extension in C. elegans

Lysosomes play important roles in cellular degradation to maintain cell homeostasis. In order to understand whether and how lysosomes alter with age and contribute to lifespan regulation, we characterized multiple properties of lysosomes during the aging process in C. elegans. We uncovered age-depen...

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Bibliographic Details
Main Authors: Yanan Sun, Meijiao Li, Dongfeng Zhao, Xin Li, Chonglin Yang, Xiaochen Wang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/55745