Guanylate-binding proteins induce apoptosis of leukemia cells by regulating MCL-1 and BAK
Abstract Interferon-inducible guanylate-binding proteins (GBPs) are well-known for mediating host-defense mechanisms against cellular pathogens. Emerging evidence suggests that GBPs are also implicated in tumorigenesis; however, their underlying molecular mechanism is still unknown. In this study, w...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2021-07-01
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| Series: | Oncogenesis |
| Online Access: | https://doi.org/10.1038/s41389-021-00341-y |