Age-Dependent Cancer Risk Is Not Different in between MSH2 and MLH1 Mutation Carriers

Age-Dependent Cancer Risk Is Not Different in between MSH2 and MLH1 Mutation Carriers

Lynch syndrome is mostly characterized by early-onset colorectal and endometrial adenocarcinomas. Over 90% of the causal mutations occur in two mismatch repair genes, MSH2 and MLH1. The aim of this study was to evaluate the age-dependent cancer risk in MSH2 or MLH1 mutation carriers from data of DNA...

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Bibliographic Details
Main Authors: Sylviane Olschwang, Kai Yu, Christine Lasset, Stéphanie Baert-Desurmont, Marie-Pierre Buisine, Qing Wang, Pierre Hutter, Etienne Rouleau, Olivier Caron, Violaine Bourdon, Gilles Thomas
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Journal of Cancer Epidemiology
Online Access:http://dx.doi.org/10.1155/2009/791754

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http://dx.doi.org/10.1155/2009/791754

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