Minocycline synergizes with N-acetylcysteine and improves cognition and memory following traumatic brain injury in rats.

BACKGROUND: There are no drugs presently available to treat traumatic brain injury (TBI). A variety of single drugs have failed clinical trials suggesting a role for drug combinations. Drug combinations acting synergistically often provide the greatest combination of potency and safety. The drugs ex...

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Bibliographic Details
Main Authors: Samah G Abdel Baki, Ben Schwab, Margalit Haber, André A Fenton, Peter J Bergold
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2930858?pdf=render