Importance of monitoring arsenic methylation metabolism in acute promyelocytic leukemia patients receiving the treatment of arsenic trioxide

Importance of monitoring arsenic methylation metabolism in acute promyelocytic leukemia patients receiving the treatment of arsenic trioxide

Abstract Background Arsenic trioxide [ATO, inorganic arsenite (iAsIII) in solution] plays an important role in the treatment of acute promyelocytic leukemia (APL). However, the long-term adverse effects (AEs) and the retention of arsenic among APL patients are rarely reported. In this study, we focu...

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Bibliographic Details
Main Authors: Yu Zheng, Yuan-Fei Mao, Hui-Jin Zhao, Li Chen, Li-Ning Wang, Yun-Xiang Zhang, Jiong Hu, Jun-Min Li, Xiao-Yang Li, Hong-Ming Zhu
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Experimental Hematology & Oncology
Subjects:
Arsenic trioxide
Arsenic speciation
Arsenic methylation metabolism
Online Access:https://doi.org/10.1186/s40164-021-00205-6

Internet

https://doi.org/10.1186/s40164-021-00205-6

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