Mining the unknown: a systems approach to metabolite identification combining genetic and metabolic information.

Recent genome-wide association studies (GWAS) with metabolomics data linked genetic variation in the human genome to differences in individual metabolite levels. A strong relevance of this metabolic individuality for biomedical and pharmaceutical research has been reported. However, a considerable a...

Full description

Bibliographic Details
Main Authors: Jan Krumsiek, Karsten Suhre, Anne M Evans, Matthew W Mitchell, Robert P Mohney, Michael V Milburn, Brigitte Wägele, Werner Römisch-Margl, Thomas Illig, Jerzy Adamski, Christian Gieger, Fabian J Theis, Gabi Kastenmüller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3475673?pdf=render