Rationale and design of the EMPYREAN study

Abstract Aims A sodium glucose cotransporter 2 (SGLT2) inhibitor was recently found to reduce heart failure hospitalization in the EMPA‐REG OUTCOME trial. We have hypothesized that autonomic nerve activity may be modulated by SGLT2 inhibition. The current study aims to investigate the impact of empa...

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Bibliographic Details
Main Authors: Hirohiko Motoki, Izuru Masuda, Shinji Yasuno, Koji Oba, Wataru Shoin, Satoru Usami, Yoshihiko Saito, Masako Waki, Mitsuhisa Komatsu, Kenji Ueshima, Yasuaki Nakagawa, Cheol Son, Shin Yonemitsu, Shinya Hiramitsu, Manako Konda, Katsuya Onishi, Koichiro Kuwahara
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:ESC Heart Failure
Subjects:
Online Access:https://doi.org/10.1002/ehf2.12825