Loganin inhibits macrophage M1 polarization and modulates sirt1/NF-κB signaling pathway to attenuate ulcerative colitis

Loganin inhibits macrophage M1 polarization and modulates sirt1/NF-κB signaling pathway to attenuate ulcerative colitis

Loganin, a major bioactive iridoid glycoside derived from Cornus officinalis, exerts different beneficial biological properties. Recently, loganin has been reported to exhibit potential anti-inflammatory effects in the intestinal tissues, while the detailed mechanisms remain elusive. This study aime...

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Bibliographic Details
Main Authors: Shi Liu, Hui Shen, Jiyan Li, Ying Gong, Haidong Bao, Jingyuan Zhang, Lanqing Hu, Zhengpeng Wang, Jian Gong
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Bioengineered
Subjects:
loganin
ulcerative colitis
macrophage m1 polarization
sirt1/nf-κb signaling pathway
Online Access:http://dx.doi.org/10.1080/21655979.2020.1774992

Internet

http://dx.doi.org/10.1080/21655979.2020.1774992

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