The Synthetic Curcumin Analog HO-3867 Rescues Suppression of PLAC1 Expression in Ovarian Cancer Cells

Elevated expression of placenta-specific protein 1 (PLAC1) is associated with the increased proliferation and invasiveness of a variety of human cancers, including ovarian cancer. Recent studies have shown that the tumor suppressor p53 directly suppresses PLAC1 transcription. However, mutations in p...

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Bibliographic Details
Main Authors: Eric J. Devor, Brandon M. Schickling, Jace R. Lapierre, David P. Bender, Jesus Gonzalez-Bosquet, Kimberly K. Leslie
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceuticals
Subjects:
p53
Online Access:https://www.mdpi.com/1424-8247/14/9/942