High Levels of TNF-α and TIM-3 as a Biomarker of Immune Reconstitution Inflammatory Syndrome in People with HIV Infection

Immune reconstitution inflammatory syndrome (IRIS) is an exacerbated immune response that can occur to HIV+ patients after initiating antiretroviral therapy (ART). IRIS pathogenesis is unclear, but dysfunctional and exhausted cells have been reported in IRIS patients, and the TIM-3/Gal-9 axis has be...

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Bibliographic Details
Main Authors: Lucero A. Ramon-Luing, Ranferi Ocaña-Guzman, Norma A. Téllez-Navarrete, Mario Preciado-García, Dámaris P. Romero-Rodríguez, Enrique Espinosa, Gustavo Reyes-Terán, Leslie Chavez-Galan
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Life
Subjects:
HIV
Online Access:https://www.mdpi.com/2075-1729/11/6/527