Osteogenic growth peptide-loaded 3D-printed PCL scaffolds for the promotion of osteogenesis through the ERK pathway

Osteogenic growth peptide-loaded 3D-printed PCL scaffolds for the promotion of osteogenesis through the ERK pathway

This study aims to improve the osteogenic differentiation in vitro and bone formation in vivo through polycaprolactone (PCL) scaffolds modified with the osteogenic growth peptide (OGP). Three-dimensional (3D)-printed PCL scaffolds were designed with computer-aided design (CAD) software and fabricate...

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Bibliographic Details
Main Authors: Qing Wang, Xiaojie Yang, Guangfei Wang, Leilei Wan, Shiwei Wang, Xiaoyong Niu, Jiannan Wu, Jinsong Pan
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Materials & Design
Subjects:
Polycaprolactone
1,6-hexamethylenediamine
Bone marrow-derived stem cells
Osteogenic growth peptide
Osteogenic differentiation
Cranial defect model
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127520303452

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http://www.sciencedirect.com/science/article/pii/S0264127520303452

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