Establishment of a yeast-based VLP platform for antigen presentation

Establishment of a yeast-based VLP platform for antigen presentation

Abstract Background Chimeric virus-like particles (VLP) allow the display of foreign antigens on their surface and have proved valuable in the development of safe subunit vaccines or drug delivery. However, finding an inexpensive production system and a VLP scaffold that allows stable incorporation...

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Bibliographic Details
Main Authors: David Wetzel, Theresa Rolf, Manfred Suckow, Andreas Kranz, Andreas Barbian, Jo-Anne Chan, Joachim Leitsch, Michael Weniger, Volker Jenzelewski, Betty Kouskousis, Catherine Palmer, James G. Beeson, Gerhard Schembecker, Juliane Merz, Michael Piontek
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Microbial Cell Factories
Subjects:
Virus-like particles
Chimeric virus-like particles
Antigen presentation
DHBV
Animal infectious diseases
Hansenula polymorpha
Online Access:http://link.springer.com/article/10.1186/s12934-018-0868-0

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http://link.springer.com/article/10.1186/s12934-018-0868-0

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