The level of microRNA 21 is upregulated by rapamycin in serum of tuberous sclerosis complex patients and subependymal giant cell astrocytoma (SEGA)-derived cell cultures

Tuberous sclerosis complex (TSC) represents a genetic condition, in which the clinical manifestations are caused by the disinhibition of the mammalian target of rapamycin (mTOR) pathway due to mutations in the TSC1 (hamartin) or TSC2 (tuberin) genes. The deregulated mTOR activity leads to multi-site...

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Bibliographic Details
Main Authors: Bozena Kuzniewska, Krzysztof Sadowski, Katarzyna Urbanska, Malgorzata Urbanska, Katarzyna Kotulska, Ewa Liszewska, Wieslawa Grajkowska, Sergiusz Jóźwiak, Magdalena Dziembowska
Format: Article
Language:English
Published: Termedia Publishing House 2018-09-01
Series:Folia Neuropathologica
Subjects:
Online Access:https://www.termedia.pl/The-level-of-microRNA-21-is-upregulated-by-rapamycin-in-serum-of-tuberous-sclerosis-complex-patients-and-subependymal-giant-cell-astrocytoma-SEGA-derived-cell-cultures,20,33880,1,1.html