Glutaredoxin2 isoform b (Glrx2b) promotes RANKL-induced osteoclastogenesis through activation of the p38-MAPK signaling pathway

Glutaredoxin2 isoform b (Glrx2b) promotes RANKL-induced osteoclastogenesis through activation of the p38-MAPK signaling pathway

Receptor activator of NF-κB ligand (RANKL) triggers thedifferentiation of bone marrow-derived monocyte/macrophageprecursor cells (BMMs) of hematopoietic origin into osteoclaststhrough the activation of mitogen-activated protein (MAP) kinasesand transcription factors. Recently, reactive oxygen specie...

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Bibliographic Details
Main Authors: Jeong-Tae Yeon, Sik-Won Choi, Kie-In Park, Min-Kyu Choi, Jeong-Joong Kim, Byung-Soo Youn, Myeung Su Lee, Jaemin Oh
Format: Article
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2012-03-01
Series:BMB Reports
Subjects:
Glrx2b
Glutaredoxin2 isoform b
Osteoclasts
p38
RANKL
Online Access:http://bmbreports.org/jbmb/pdf.php?data=MTMxMTA4MTZAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS0zJTVEMTIwMzI3MTU0Nl8lMjgxNzEtMTc2JTI5Qk1CXzExLTIyNy5wZGY=

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http://bmbreports.org/jbmb/pdf.php?data=MTMxMTA4MTZAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS0zJTVEMTIwMzI3MTU0Nl8lMjgxNzEtMTc2JTI5Qk1CXzExLTIyNy5wZGY=

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