A physiologically based in silico kinetic model predicting plasma cholesterol concentrations in humans[S]

Increased plasma cholesterol concentration is associated with increased risk of cardiovascular disease. This study describes the development, validation, and analysis of a physiologically based kinetic (PBK) model for the prediction of plasma cholesterol concentrations in humans. This model was dire...

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Bibliographic Details
Main Authors: Niek C.A. van de Pas, Ruud A. Woutersen, Ben van Ommen, Ivonne M. C.M. Rietjens, Albert A. de Graaf
Format: Article
Language:English
Published: Elsevier 2012-12-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520418085