Alkaline Phosphatases Account for Low Plasma Levels of Inorganic Pyrophosphate in Chronic Kidney Disease

Alkaline Phosphatases Account for Low Plasma Levels of Inorganic Pyrophosphate in Chronic Kidney Disease

IntroductionPatients on dialysis and kidney transplant recipients (KTR) present the syndrome of mineral and bone disorders (MBD), which share common traits with monogenic calcifying diseases related to disturbances of the purinergic system. Low plasma levels of inorganic pyrophosphate (PPi) and ecto...

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Bibliographic Details
Main Authors: Audrey Laurain, Isabelle Rubera, Christophe Duranton, Frank Rutsch, Yvonne Nitschke, Elodie Ray, Sandor Vido, Antoine Sicard, Georges Lefthériotis, Guillaume Favre
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
alkaline phosphatase activity
hemodialysis
kidney transplant
pyrophosphate
purinergic mechanisms
mineral and bone disorder (CKD-MBD)
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.586831/full

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https://www.frontiersin.org/articles/10.3389/fcell.2020.586831/full

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