MiRNA Regulation of MIF in SLE and Attenuation of Murine Lupus Nephritis With miR-654

Objective: Macrophage Migration Inhibitory Factor (MIF) is involved in the pathogenesis of systemic lupus erythematosus (SLE) and lupus nephritis (LN). MicroRNAs (miRNAs) play important roles in LN but whether specific miRNAs regulate the expression of MIF in LN is unknown. We explore specific miRNA...

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Bibliographic Details
Main Authors: Yang Tu, Ruru Guo, Jia Li, Suli Wang, Lin Leng, Jun Deng, Richard Bucala, Liangjing Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
MIF
SLE
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02229/full