Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide

Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide

<p>Abstract</p> <p>Background</p> <p>Hypoxia-inducible factor-1α (HIF-1α), a critical transcription factor to reduced O<sub>2 </sub>availability, has been demonstrated to be extensively involved in tumor survival, aggressive progression, drug resistance and...

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Bibliographic Details
Main Authors: Li Zheng, Tong Lin-Jiang, Dai Mei, Feng Jian-Ming, Chen Yi, Jiang Yi, Yu Bing, Luo Zhi-Guo, Zhou Zhao-Li, Li Yuan-Chao, Ding Jian, Miao Ze-Hong
Format: Article
Language:English
Published: BMC 2010-10-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/268

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http://www.molecular-cancer.com/content/9/1/268

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