HLA Class II Antigens and Their Interactive Effect on Perinatal Mother-To-Child HIV-1 Transmission.

HLA class II antigens are central in initiating antigen-specific CD4+ T cell responses to HIV-1. Specific alleles have been associated with differential responses to HIV-1 infection and disease among adults. This study aims to determine the influence of HLA class II genes and their interactive effec...

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Bibliographic Details
Main Authors: Ma Luo, Joanne Embree, Suzie Ramdahin, Thomas Bielawny, Tyler Laycock, Jeffrey Tuff, Darren Haber, Mariel Plummer, Francis A Plummer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4422511?pdf=render