Strong, Long-Term Transgene Expression in Rat Liver Using Chicken β-Actin Promoter Associated with Cytomegalovirus Immediate-Early Enhancer (CAG Promoter)
For successful gene therapy in hepatic enzyme deficiencies, it is essential to use promoters that can maintain strong transcriptional activity for the long term in the liver. Using Gunn rats, a model animal for Crigler-Najjar syndrome type I, the long-term transcriptional function of the CAG promote...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2000-09-01
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| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.1177/096368970000900513 |