Primary and Immortalized Human Respiratory Cells Display Different Patterns of Cytotoxicity and Cytokine Release upon Exposure to Deoxynivalenol, Nivalenol and Fusarenon-X

Primary and Immortalized Human Respiratory Cells Display Different Patterns of Cytotoxicity and Cytokine Release upon Exposure to Deoxynivalenol, Nivalenol and Fusarenon-X

The type B trichothecene mycotoxins deoxynivalenol (DON), nivalenol (NIV) and fusarenon-X (FX) are structurally related secondary metabolites frequently produced by Fusarium on wheat. Consequently, DON, NIV and FX contaminate wheat dusts, exposing grain workers to toxins by inhalation. Those trichot...

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Bibliographic Details
Main Authors: Silvia Ferreira Lopes, Gaëlle Vacher, Eleonora Ciarlo, Dessislava Savova-Bianchi, Thierry Roger, Hélène Niculita-Hirzel
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Toxins
Subjects:
mycotoxins
deoxynivalenol
nivalenol
fusarenon
airway epithelial cells
cytotoxicity
cytokine
Online Access:https://www.mdpi.com/2072-6651/9/11/337

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https://www.mdpi.com/2072-6651/9/11/337

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