Primary and Immortalized Human Respiratory Cells Display Different Patterns of Cytotoxicity and Cytokine Release upon Exposure to Deoxynivalenol, Nivalenol and Fusarenon-X

Primary and Immortalized Human Respiratory Cells Display Different Patterns of Cytotoxicity and Cytokine Release upon Exposure to Deoxynivalenol, Nivalenol and Fusarenon-X

The type B trichothecene mycotoxins deoxynivalenol (DON), nivalenol (NIV) and fusarenon-X (FX) are structurally related secondary metabolites frequently produced by Fusarium on wheat. Consequently, DON, NIV and FX contaminate wheat dusts, exposing grain workers to toxins by inhalation. Those trichot...

Full description

Bibliographic Details
Main Authors: Silvia Ferreira Lopes, Gaëlle Vacher, Eleonora Ciarlo, Dessislava Savova-Bianchi, Thierry Roger, Hélène Niculita-Hirzel
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Toxins
Subjects:
mycotoxins
deoxynivalenol
nivalenol
fusarenon
airway epithelial cells
cytotoxicity
cytokine
Online Access:https://www.mdpi.com/2072-6651/9/11/337

Similar Items

Similar Items