Reprogramming of basic metabolic pathways in microbial sepsis: therapeutic targets at last?

Abstract Sepsis is a highly lethal and urgent unmet medical need. It is the result of a complex interplay of several pathways, including inflammation, immune activation, hypoxia, and metabolic reprogramming. Specifically, the regulation and the impact of the latter have become better understood in w...

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Bibliographic Details
Main Authors: Lise Van Wyngene, Jolien Vandewalle, Claude Libert
Format: Article
Language:English
Published: Wiley 2018-08-01
Series:EMBO Molecular Medicine
Subjects:
Online Access:https://doi.org/10.15252/emmm.201708712