PTEN loss increases PD-L1 protein expression and affects the correlation between PD-L1 expression and clinical parameters in colorectal cancer.

PTEN loss increases PD-L1 protein expression and affects the correlation between PD-L1 expression and clinical parameters in colorectal cancer.

Programmed death ligand-1 (PD-L1) has been identified as a factor associated with poor prognosis in a range of cancers, and was reported to be mainly induced by PTEN loss in gliomas. However, the clinical effect of PD-L1 and its regulation by PTEN has not yet been determined in colorectal cancer (CR...

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Bibliographic Details
Main Authors: Minmin Song, Defeng Chen, Biyan Lu, Chenliang Wang, Junxiao Zhang, Lanlan Huang, Xiaoyan Wang, Christine L Timmons, Jun Hu, Bindong Liu, Xiaojian Wu, Lei Wang, Jianping Wang, Huanliang Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3681867?pdf=render

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http://europepmc.org/articles/PMC3681867?pdf=render

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