Repeat-mediated genetic and epigenetic changes at the FMR1 locus in the Fragile X-related disorders

Repeat-mediated genetic and epigenetic changes at the FMR1 locus in the Fragile X-related disorders

AbstractThe Fragile X-related disorders are a group of genetic conditions that include the neurodegenerative disorder, Fragile X-associated tremor and ataxia syndrome (FXTAS), the fertility disorder, Fragile X-associated primary ovarian insufficiency (FXPOI) and the intellectual disability, Fragile...

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Bibliographic Details
Main Authors: Karen eUsdin, Bruce Eliot Hayward, Daman eKumari, Rachel Adihe Lokanga, Nicolas eSciascia, Xiao-Nan eZhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Genetics
Subjects:
Chromosome Fragility
epigenetics
fragile X syndrome (FXS)
Fragile X-associated tremor and ataxia syndrome
Fragile X-associated primary ovarian insufficiency
Fragile X-related disorders
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00226/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00226/full

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