Prognostic significance of cyclin D1 expression in colorectal cancer: a meta-analysis of observational studies.

OBJECTIVE: Cyclin D1 plays a vital role in cancer cell cycle progression and is overexpressed in many human cancers, including colorectal cancer (CRC). However, the prognostic value of cyclin D1 overexpression in colorectal cancer is conflicting and heterogeneous. We conducted a meta-analysis to mor...

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Bibliographic Details
Main Authors: Yang Li, Jun Wei, Chuanhui Xu, Zhongxin Zhao, Tiangeng You
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3984178?pdf=render