Assessing the Relationship Between Leukocyte Telomere Length and Cancer Risk/Mortality in UK Biobank and TCGA Datasets With the Genetic Risk Score and Mendelian Randomization Approaches

Assessing the Relationship Between Leukocyte Telomere Length and Cancer Risk/Mortality in UK Biobank and TCGA Datasets With the Genetic Risk Score and Mendelian Randomization Approaches

BackgroundTelomere length is an important indicator of tumor progression and survival for cancer patients. Previous work investigated the associations between genetically predicted telomere length and cancers; however, the types of cancers investigated in those studies were relatively limited or the...

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Bibliographic Details
Main Authors: Yixin Gao, Yongyue Wei, Xiang Zhou, Shuiping Huang, Huashuo Zhao, Ping Zeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Genetics
Subjects:
leukocyte telomere length
cancer
genetic risk score
UK Biobank
TCGA
Mendelian randomization
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.583106/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2020.583106/full

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