Diseases of the nERVous system: retrotransposon activity in neurodegenerative disease

Diseases of the nERVous system: retrotransposon activity in neurodegenerative disease

Abstract Transposable Elements (TEs) are mobile genetic elements whose sequences constitute nearly half of the human genome. Each TE copy can be present in hundreds to thousands of locations within the genome, complicating the genetic and genomic studies of these highly repetitive sequences. The rec...

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Bibliographic Details
Main Authors: Oliver H. Tam, Lyle W. Ostrow, Molly Gale Hammell
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Mobile DNA
Subjects:
Transposable elements
Endogenous retroviruses
Neurodegenerative disease
Amyotrophic lateral sclerosis
Alzheimer’s disease
Aicardi-Goutieres syndrome
Online Access:http://link.springer.com/article/10.1186/s13100-019-0176-1

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http://link.springer.com/article/10.1186/s13100-019-0176-1

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